Dimensions

PlumX

How to Cite
Bambú Jaén, A. G., Hernández Taton, A. A., & Loaiza Valladares, B. A. (2025). Advances in the application of high-dose-rate brachytherapy in patients with gynecological cancer: a theoretical review and imaging approach. Saluta, 1(12), 70–96. https://doi.org/10.37594/saluta.v1i12.1806
License terms

Manuscripts sent to SALUTA Magazine must be original and unpublished and must not be simultaneously in the process of publication in other magazines, compilations or any other means of publication. The content of the publications and the links suggested in them are the sole responsibility of the authors and not of the METROPOLITAN UNIVERSITY OF EDUCATION, SCIENCE AND TECHNOLOGY

(UMECIT) or the magazine SALUTA. They are protected by international copyright laws as well as the logos of UMECIT AND SALUTA MAGAZINE, hence their reproduction is totally prohibited. The copyright will belong to the UMECIT.

Under a Creative Commons Attribution License  authors may share work with acknowledgment of authorship of the work and initial publication in this journal.

                                                               

Abstract

This article analyzes the role of imaging in planning high-dose-rate brachytherapy in patients with gynecological cancer and the advances in this treatment for the benefit of patients. In Panama, gynecological cancer is one of the most common cancers nationwide. Therefore, it is considered necessary to understand the most favorable protocols for brachytherapy treatment. A theoretical review was carried out on the use of imaging in high-dose-rate brachytherapy as a treatment for gynecological cancer and in this way to know which imaging technique was considered the most viable, for this, documentary collection was used as a technique and a bibliographic matrix was implemented as a data collection instrument where information from five studies published between 2020 and 2025 was collected. It was observed that imaging is a fundamental part in the treatment planning of high-dose-rate brachytherapy in gynecological cancer, part of this includes the prior evaluation of the patient that allows knowing the extent of the disease, determining the amount of dose and its distribution, the delimitation of the target volumes such as the macroscopic tumor volume or the clinical treatment volume, and the organs at risk. Computed tomography (CT) and magnetic resonance imaging (MRI) are suitable methods for determining organs at risk and delineating target volumes. However, the authors emphasize their preference over MRI due to their greater soft tissue resolution and anatomical accuracy. Over time, new techniques have been introduced to enhance treatment, such as the development of 3D Image-Guided Brachytherapy (3DIGBT), single-dose multifractionated brachytherapy, and systems such as the Interactive Optimization Interface (IOI).

References

Academia Lab. (16 de Mayo de 2025). Academia Lab. Obtenido de Marcador fiducial: https://academia-lab.com/enciclopedia/marcador-fiducial/ [20]

Bandyopadhyay, A., Ghosh, K. A., Chhatui, B., & Das, D. (14 de Abril de 2021). Dosimetric and clinical outcomes of CT based HR-CTV delineation for HDR intracavitary brachytherapy in carcinoma cervix — a retrospective study. Obtenido de National Library of Medicine: https://pmc.ncbi.nlm.nih.gov/articles/PMC8241309/ [11]

Bobadilla, I. A., & Martínez Pérez, D. A. (2023). BRAQUITERAPIA, UN TRATAMIENTO DE ALTA PRECISIÓN CONTRA EL CÁNCER. Revista Momentos , párr. 8-13. [15]

Chopra, S., Mulani, J., Mittal, P., Singh, M., Shinde, A., Gurram, L., y otros. (2 de Noviembre de 2022). Early outcomes of abbreviated multi-fractionated brachytherapy schedule for cervix cancer during COVID-19 pandemic. Obtenido de National Library Of Medicine : https://pmc.ncbi.nlm.nih.gov/articles/PMC9626438/ [10]

Clínica Universidad de Navarra. (2023). Técnica de imagen digital. Obtenido de Clínica Universidad de Navarra: https://www.cun.es/diccionario-medico/terminos/tecnica-de-imagen-digital#:~:text=La%20t%C3%A9cnica%20de%20imagen%20digital%20en%20medicina%20es%20un%20avance,procesar%20y%20visualizar%20im%C3%A1genes%20m%C3%A9dicas. [8]

Clínica Universidad de Navarra. (2023). Topograma. Obtenido de Clínica Universidad de Navarra: https://www.cun.es/diccionario-medico/terminos/topograma [18]

Fundación Instituto Roche. (s.f.). Actualización en investigación clínica Glosario de términos. Obtenido de Fundación Instituto Roche: https://www.institutoroche.es/jornadas/static/jornadas/archivos/Glosario_EECC_seminario_FIR-ANIS.pdf [12]

Kadirus, A. S., Othman, A. S., & Ridzuan, A. N. (Enero de 2023). Remote Afterloading Technology: A Short Review. Obtenido de ResearchGate: https://www.researchgate.net/publication/371873840_Remote_Afterloading_Technology_A_Short_Review [16]

Law, M. Y., Liu, B., & Chan, L. W. (2009). Informatics in radiology: DICOM-RT-based electronic patient record information system for radiation therapy. RadioGraphics , 29 (4), 961-72. [13]

Liu, H., Ma, C. M., Jia, X., Shen, C., Klages, P., & Albuquerque, K. (2021). Interactive Treatment Planning in High Dose-Rate Brachytherapy for Gynecological Cancer. arXiv. doi:https://doi.org/10.48550/arXiv.2109.05081 [4]

Mafraji, A. M. (Noviembre de 2023). Resonancia Magnética. Obtenido de Manual MSD: https://www.msdmanuals.com/es/professional/temas-especiales/principios-de-estudios-por-la-imagen-radiol%C3%B3gicas/resonancia-magn%C3%A9tica [19]

Mahantshetty, U., Gurram, L., Bushra, S., Ghadi, Y., Aravindakshan, D., Paul, J., y otros. (2021). Single Application Multifractionated Image Guided Adaptive High-Dose-Rate Brachytherapy for Cervical Cancer: Dosimetric and Clinical Outcomes. International Journal of Radiation Oncology - Biology - Physics , 111 (3), 826-834. [3]

NIH Instituto Nacional del cáncer. (s.f.). Diccionario de cáncer del NCI. Obtenido de https://www.cancer.gov/espanol/publicaciones/diccionarios/diccionario-cancer/def/supervivencia-por-causa-especifica [9]

ONCOSERVICE. (s.f.). Braquiterapia de Alta Tasa de Dosis – 3D Conformada. Obtenido de ONCOSERVICE: https://oncoservice.bo/braqui-3d/#:~:text=Braquiterapia%203D%20se%20define%20como,a%20los%20tejidos%20sanos%20proximos [7]

Rayos Contra Cancer. (6 de Junio de 2022). Sesión 9 - Aplicadores y usos. Fabiola Valencia enseña Sesión 9 - “Aplicadores y usos” del curso de HDR Braquiterapia para físicos médicos, organizado por Rayos Contra Cancer. [17]

Rovirosa, À., Samper, P., & Villafranca, E. (Enero de 2022). Braquiterapia 3D guiada por la imagen. Obtenido de Sociedad Española De Oncología Radioterápica: https://seor.es/wp-content/uploads/2023/01/AAFF_Braquiterapia_libro.pdf [5]

Sandwall, A. P., Feng, Y., Platt, M., Lamba, M., & Mahalingam, S. (2018). Evolution of brachytherapy treatment planning to deterministic radiation transport for calculation of cardiac dose. Obtenido de ScienceDirect: https://www.sciencedirect.com/science/article/abs/pii/S0958394718300323 [14]

Solis, J. A., Olivares, J., Tudela, B., Veillon, G., Perrot, I., & Lazcano, G. (2020). Braquiterapia adaptativa guiada por resonancia magnética para el cáncer cervical localmente avanzado: Experiencia del Hospital Carlos Van Buren. Revista Chilena de Obstetricia y Ginecología, 85 (6), 604-616. [6]

Urdaneta, N., Reyes, R., Abreu, P., Aguirre, L., Rodríguez, H., Lira, L., y otros. (2024). BRAQUITERAPIA GUIADA POR IMÁGENES CON PLANIFICACIÓN 3D EN CÁNCER DE CUELLO UTERINO. EXPERIENCIA PRELIMINAR. Revista Venezolana de Oncología , 37 (1), 16-36. [2]

WHO. (2024). Cervical cancer. Obtenido de World Health Oranization: https://www.who.int/health-topics/cervical-cancer#tab=tab_1 [1]

Downloads

Download data is not yet available.

Publication Facts

Metric
This article
Other articles
Peer reviewers 
0
2.4

Reviewer profiles  N/A

Author statements

Author statements
This article
Other articles
Data availability 
N/A
16%
External funding 
No
32%
Competing interests 
N/A
11%
Metric
This journal
Other journals
Articles accepted 
38%
33%
Days to publication 
17
145

Indexed in

Editor & editorial board
profiles
Publisher 
Universidad Metropolitana de Educación, Ciencia y Tecnología